2'-Deoxyadenosine-15N1 is a stable isotope-labeled variant of 2'-Deoxyadenosine, primarily utilized in metabolic labeling studies. It exerts a biological effect by inhibiting glucose-stimulated insulin release and impeding cAMP accumulation in pancreatic islets. Additionally, 2'-Deoxyadenosine-15N1 activates caspase-3, promoting apoptosis, and inhibits the enzyme S-adenosyl-L-homocysteine hydrolase (SAHH). Its cell growth inhibition properties suggest potential applications in cancer research, particularly in studying its effects on colon cancer cell lines.
2'-Deoxyadenosine-15N1 is a stable isotope-labeled variant of 2'-Deoxyadenosine, primarily utilized in metabolic labeling studies. It exerts a biological effect by inhibiting glucose-stimulated insulin release and impeding cAMP accumulation in pancreatic islets. Additionally, 2'-Deoxyadenosine-15N1 activates caspase-3, promoting apoptosis, and inhibits the enzyme S-adenosyl-L-homocysteine hydrolase (SAHH). Its cell growth inhibition properties suggest potential applications in cancer research, particularly in studying its effects on colon cancer cell lines.
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