2'-Deoxyadenosine monohydrate-1′-13C is a stable isotope-labeled version of 2'-Deoxyadenosine monohydrate that primarily targets nucleotide metabolism. This compound exhibits significant biological activity by inhibiting glucose-stimulated insulin release and decreasing cyclic AMP (cAMP) accumulation in pancreatic islets. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH), thereby impacting cell growth. Its potential anticancer properties have been observed in colon cancer research, making it a valuable tool for investigations into nucleotide signaling and cancer biology.
2'-Deoxyadenosine monohydrate-1′-13C is a stable isotope-labeled version of 2'-Deoxyadenosine monohydrate that primarily targets nucleotide metabolism. This compound exhibits significant biological activity by inhibiting glucose-stimulated insulin release and decreasing cyclic AMP (cAMP) accumulation in pancreatic islets. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH), thereby impacting cell growth. Its potential anticancer properties have been observed in colon cancer research, making it a valuable tool for investigations into nucleotide signaling and cancer biology.
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