2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate is a stable isotope-labeled variant of 2'-Deoxyadenosine monohydrate, incorporating both carbon-13 and nitrogen-15. This nucleoside is known to inhibit glucose-stimulated insulin release by affecting islet cyclic AMP (cAMP) levels. Additionally, it activates caspase-3, promoting apoptosis, and demonstrates inhibition of S-adenosyl-L-homocysteine hydrolase (SAHH). Research applications include studying cellular growth inhibition and evaluating anticancer effects, particularly in colon cancer models.
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate is a stable isotope-labeled variant of 2'-Deoxyadenosine monohydrate, incorporating both carbon-13 and nitrogen-15. This nucleoside is known to inhibit glucose-stimulated insulin release by affecting islet cyclic AMP (cAMP) levels. Additionally, it activates caspase-3, promoting apoptosis, and demonstrates inhibition of S-adenosyl-L-homocysteine hydrolase (SAHH). Research applications include studying cellular growth inhibition and evaluating anticancer effects, particularly in colon cancer models.
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