Fig. 1 · Structure
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2'-Deoxyadenosine monohydrate
Adenine Nucleoside
2'-Deoxyadenosine monohydrate is an adenine nucleoside that primarily targets glucose-stimulated insulin secretion. It effectively inhibits glucose-induced increases in islet cyclic AMP (cAMP) levels and activates caspase-3, promoting apoptosis. Additionally, it functions as an inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH) and exhibits growth inhibitory effects on various cell types. Notably, 2'-Deoxyadenosine monohydrate demonstrates anticancer activity against colon cancer, making it a valuable tool for research in cellular signaling and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 16373-93-6 |
| Applications | Adenine Nucleoside |
| Formula | C10H15N5O4 |
| Molecular Weight | 269.26 |
| SMILES | O[C@H]1C[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.