Fig. 1 · Structure
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2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
Cytidine Analog
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog that inhibits DNA methyltransferases, thereby influencing gene expression and cellular metabolism. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research and epigenetic studies. Its unique structure allows for incorporation into nucleic acids, facilitating investigations into gene regulation and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1404463-12-2 |
| Applications | Cytidine Analog |
| Formula | C46H51FN5O8P |
| Molecular Weight | 851.90 |
| SMILES | O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.