2-Hexyl-4-pentynoic acid serves as an HDAC inhibitor, demonstrating an IC50 value of 13 μM. This compound induces HSP70 expression and promotes histone hyperacetylation, providing neuroprotection against glutamate-induced excitotoxicity in cultured neurons. Additionally, it is utilized in breast carcinoma research and acts as a click chemistry reagent, featuring an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
2-Hexyl-4-pentynoic acid serves as an HDAC inhibitor, demonstrating an IC50 value of 13 μM. This compound induces HSP70 expression and promotes histone hyperacetylation, providing neuroprotection against glutamate-induced excitotoxicity in cultured neurons. Additionally, it is utilized in breast carcinoma research and acts as a click chemistry reagent, featuring an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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