2-Iodomelatonin is a selective agonist of the melatonin receptor 1 (MT1), exhibiting a potent Ki value of 28 pM and a more than five-fold preference for MT1 over MT2. This compound is valuable for identifying, characterizing, and localizing melatonin binding sites in both brain and peripheral tissues. Its application in research facilitates the study of melatonin’s role in various physiological processes and may aid in the investigation of related disorders.
2-Iodomelatonin is a selective agonist of the melatonin receptor 1 (MT1), exhibiting a potent Ki value of 28 pM and a more than five-fold preference for MT1 over MT2. This compound is valuable for identifying, characterizing, and localizing melatonin binding sites in both brain and peripheral tissues. Its application in research facilitates the study of melatonin’s role in various physiological processes and may aid in the investigation of related disorders.
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