Fig. 1 · Structure
Documents & Downloads
2-Ketoglutaric acid
Krebs Cycle Intermediate
2-Ketoglutaric acid, a critical intermediate in the Krebs cycle, plays a vital role in the production of ATP and GTP. It serves as the primary carbon skeleton for nitrogen-assimilatory reactions, facilitating essential metabolic processes. Additionally, 2-Ketoglutaric acid functions as a reversible inhibitor of tyrosinase, with an IC50 of 15 mM, making it useful for research into enzymatic activities and metabolic regulation.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 328-50-7 |
| Applications | Krebs Cycle Intermediate |
| Formula | C5H6O5 |
| Molecular Weight | 146.10 |
| Synonyms | Alpha-Ketoglutaric acid; 2-Oxoglutaric acid |
| SMILES | O=C(C(O)=O)CCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.