2-Methoxyestradiol
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | 2-Methoxyestradiol is an apoptotic, antiproliferative and antiangiogenic agent. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. | ||
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Catalog Num | A10012 |
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Formula | C19H26O3 |
Molecular Weight | 302.4 |
CAS Number | 362-07-2 |
SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C(OC)=C3 |
Synonyms | 2-ME2 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 55 mg/mL (181.87 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2%DMSO+30%PEG300+5%Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.07 mL | 165.34 mL | 330.69 mL |
0.5 mM | 6.61 mL | 33.07 mL | 66.14 mL |
1 mM | 3.31 mL | 16.53 mL | 33.07 mL |
5 mM | 0.66 mL | 3.31 mL | 6.61 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2