Fig. 1 · Structure
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2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid
Substrate
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid serves as a chromogenic substrate for neuraminidase. Upon enzymatic hydrolysis, it yields p-nitrophenol, facilitating the quantification of enzyme activity and the assessment of inhibitory effects through spectrophotometric analysis. Additionally, this compound functions as a sialyl donor in enzyme-catalyzed trans-sialylation processes, making it valuable for studies involving sialic acid metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 26112-88-9 |
| Applications | Substrate |
| Formula | C17H22N2O11 |
| Molecular Weight | 430.36 |
| Synonyms | PNP-α-NeuNAc |
| SMILES | O=C([C@@]1(OC2=CC=C([N+]([O-])=O)C=C2)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.