Fig. 1 · Structure
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2-(Piperidin-4-yl)ethan-1-ol
PROTAC Linker
2-(Piperidin-4-yl)ethan-1-ol is a PROTAC linker utilized in the assembly of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of proteins by linking a target protein ligand to an E3 ligase ligand, allowing for controlled modulation of protein levels in cellular systems. Its application is instrumental in drug discovery and development, particularly in studying protein function and therapeutic interventions in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 622-26-4 |
| Applications | PROTAC Linker |
| Formula | C7H15NO |
| Molecular Weight | 129.20 |
| Synonyms | 4-Piperidineethanol |
| SMILES | OCCC1CCNCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.