Fig. 1 · Structure

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21-Deoxy cortisone

Steroid Metabolite

21-Deoxy Cortisone is a corticosteroid metabolite primarily associated with the enzymatic activity of cytochrome P450 isozyme CYP17A1. This compound plays a significant role in steroid hormone biosynthesis and is relevant for understanding metabolic disorders, particularly congenital adrenal hyperplasia, where its levels are elevated due to a deficiency of 21-hydroxylase. Research applications include studies on steroid metabolism and endocrine disorders.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1882-82-2
Applications Steroid Metabolite
Formula C21H28O4
Molecular Weight 344.44
Synonyms 21-Desoxycortisone; NSC 38722
SMILES
O=C([C@@]1([C@]2(CC([C@]3([C@@]([H])(CCC4=CC(CC[C@@]43C)=O)[C@@]2(CC1)[H])[H])=O)C)O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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