Fig. 1 · Structure

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(2R,3S)-E1R

Sig1R PAM

(2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) that enhances receptor activity. This compound has demonstrated potential in the treatment of cognition and memory disorders by modulating signaling pathways associated with neuroprotection and cognitive enhancement. Its unique mechanism of action makes it a valuable tool for research in neurobiology and the development of therapies for neurodegenerative diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1424832-60-9
Applications Sig1R PAM
Formula C13H16N2O2
Molecular Weight 232.28
SMILES
O=C(N)CN1[C@H](C)[C@H](C2=CC=CC=C2)CC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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