Fig. 1 · Structure

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(2S,3S)-E1R

Sig1R PAM

(2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) that enhances cognitive and memory functions. This enantiomer of E1R is designed for research applications exploring the modulation of sigma-1 receptor activity, which has implications in treating cognition and memory disorders. Its selectivity and mechanism of action make it a valuable reagent in neuroscience studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1424832-57-4
Applications Sig1R PAM
Formula C13H16N2O2
Molecular Weight 232.28
SMILES
O=C(N)CN1[C@@H](C)[C@H](C2=CC=CC=C2)CC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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