3,5,6,7,8,3',4'-Heptemthoxyflavone is a flavonoid with potent anti-inflammatory properties, functioning as a CREB activator. This compound exhibits anti-tumor and neuroprotective activities by inhibiting collagenase activity and enhancing type I procollagen synthesis in human dermal fibroblast neoblast (HDFn) cells. Additionally, it promotes the expression of brain-derived neurotrophic factor (BDNF) via the cAMP/ERK/CREB signaling pathway and decreases phosphodiesterase activity in C6 glioma cells, making it a valuable tool for research in inflammation and neurobiology.
3,5,6,7,8,3',4'-Heptemthoxyflavone is a flavonoid with potent anti-inflammatory properties, functioning as a CREB activator. This compound exhibits anti-tumor and neuroprotective activities by inhibiting collagenase activity and enhancing type I procollagen synthesis in human dermal fibroblast neoblast (HDFn) cells. Additionally, it promotes the expression of brain-derived neurotrophic factor (BDNF) via the cAMP/ERK/CREB signaling pathway and decreases phosphodiesterase activity in C6 glioma cells, making it a valuable tool for research in inflammation and neurobiology.
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