Fig. 1 · Structure
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3,5,7,3′,4′-Pentamethoxyflavone
Ca2+ Channel Inhibitor
3,5,7,3′,4′-Pentamethoxyflavone is a Ca2+ channel inhibitor that exhibits protective effects against oxidative DNA damage. It facilitates relaxation of the human corpus cavernosum through mechanisms related to calcium mobilization and promotes the expression of endothelial nitric oxide synthase (eNOS) and cystathionine gamma-lyase (CSE) proteins in middle-aged male rats, thereby regulating vascular function. This compound is valuable for research applications in diabetes and cardiovascular diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1247-97-8 |
| Applications | Ca2+ Channel Inhibitor |
| Formula | C20H20O7 |
| Molecular Weight | 372.37 |
| SMILES | O=C1C(OC)=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(OC)=CC(OC)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.