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3’-Azido-3’-deoxy-5-methoxyuridine

Purine Nucleoside Analog

3'-Azido-3'-deoxy-5-methoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. Additionally, this compound serves as a versatile click chemistry reagent, containing an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or those featuring DBCO or BCN groups.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2095417-70-0
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₃N₅O₆
Molecular Weight	299.24
SMILES	OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N(C(N2)=O)C=C(OC)C2=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.