3’-Azido-N6-benzoyl-3’-deoxyadenosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is also a versatile click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring alkyne, DBCO, or BCN groups. Its unique properties make it valuable for various biochemical and molecular biology applications.
3’-Azido-N6-benzoyl-3’-deoxyadenosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is also a versatile click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring alkyne, DBCO, or BCN groups. Its unique properties make it valuable for various biochemical and molecular biology applications.
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