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3’-Azido-N6-benzoyl-3’-deoxyadenosine

Purine Nucleoside Analog

3’-Azido-N6-benzoyl-3’-deoxyadenosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is also a versatile click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring alkyne, DBCO, or BCN groups. Its unique properties make it valuable for various biochemical and molecular biology applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	103597-10-0
Applications	Purine Nucleoside Analog
Formula	C₁₇H₁₆N₈O₄
Molecular Weight	396.36
SMILES	OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(N=CN=C3NC(C4=CC=CC=C4)=O)=C3N=C2)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.