Fig. 1 · Structure

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3-Butyn-1-amine hydrochloride

PROTAC Linker

3-Butyn-1-amine hydrochloride serves as a critical PROTAC linker, essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the development of bifunctional molecules that can selectively degrade target proteins, enhancing research in targeted protein degradation and therapeutic applications. Its structural properties facilitate the effective incorporation into a variety of PROTAC designs, making it a valuable tool for discovery and development in chemical biology and drug development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 88211-50-1
Applications PROTAC Linker
Formula C4H8ClN
Molecular Weight 105.57
SMILES
Cl.C#CCCN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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