Fig. 1 · Structure
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3-Cyanochromone
NDM-1/VIM-2 Inhibitor
3-Cyanochromone is a dual inhibitor targeting NDM-1 and VIM-2 with KD values of 181 μM and 999 μM, respectively. This compound demonstrates significant potential in antibiotic research, contributing to the study of β-lactamase enzymes and their role in antibiotic resistance. Its unique structural properties make it a valuable tool for exploring therapeutic strategies against resistant bacterial strains.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 50743-17-4 |
| Applications | NDM-1/VIM-2 Inhibitor |
| Formula | C10H5NO2 |
| Molecular Weight | 171.16 |
| SMILES | N#CC1=COC=2C=CC=CC2C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.