Fig. 1 · Structure
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3-Deaza-2'-deoxyadenosine
Antiviral agent
3-Deaza-2'-deoxyadenosine, a nucleoside analog derived from 2'-deoxyadenosine, functions primarily as an antiviral agent. It exerts its biological activity by inhibiting RNA synthesis through its binding to ribose fragments of ribonucleotides, thus disrupting enzyme-substrate complexes and hindering chain elongation. Additionally, it can impede DNA synthesis by interacting with deoxyribose fragments, preventing DNA polymerase from incorporating nucleotides. This compound is valuable for research in antiviral therapy and nucleic acid synthesis mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 78582-17-9 |
| Applications | Antiviral agent |
| Formula | C11H14N4O3 |
| Molecular Weight | 250.25 |
| SMILES | O[C@H]1C[C@H](N2C=NC3=C2C=CN=C3N)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.