Fig. 1 · Structure
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3-Deazauridine
Uridine Analogue
3-Deazauridine is a uridine analogue that serves as a competitive inhibitor of cytidine triphosphate synthase, thus disrupting the biosynthesis of cytidine-5'-triphosphate. This compound demonstrates synergistic effects with various antineoplastic agents, enhancing their therapeutic efficacy. 3-Deazauridine is primarily utilized in cancer research to investigate its potential as a biological response modifier.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 23205-42-7 |
| Applications | Uridine Analogue |
| Formula | C10H13NO6 |
| Molecular Weight | 243.21 |
| Synonyms | NSC 126849 |
| SMILES | OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(C=C(C=C2)O)=O)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.