Fig. 1 · Structure

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3’-Deoxy-3’-fluoro-5-trifluoromethyluridine

Purine Nucleoside Analog

3’-Deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research aimed at understanding the molecular mechanisms of cancer and developing novel therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 439579-21-2
Applications Purine Nucleoside Analog
Formula C10H10F4N2O5
Molecular Weight 314.19
SMILES
F[C@H]1[C@@H](O)[C@H](N(C(N2)=O)C=C(C(F)(F)F)C2=O)O[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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