Fig. 1 · Structure
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3′-Deoxy-3′-fluoroguanosine
Antiviral Agent
3′-Deoxy-3′-fluoroguanosine serves as an antiviral agent, primarily targeting the tick-borne encephalitis virus (TBEV). This compound inhibits viral RNA synthesis by interacting with the NS5B RNA-dependent RNA polymerase (RdRp) of Hepatitis C virus (HCV), ultimately disrupting the elongation of replicating viral RNA. Its application is significant in virology research, particularly in exploring antiviral mechanisms and the development of therapeutic strategies against viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 123402-21-1 |
| Applications | Antiviral Agent |
| Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| SMILES | NC(NC1=O)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.