3′-Deoxyguanosine is a derivative of guanosine that primarily targets human purine nucleoside phosphorylase. This compound interacts through hydrogen bonding with key residues, including Glu201 and Asn243, and exhibits moderate displacement activity for [3H]-guanosine in rat meninges. 3′-Deoxyguanosine is valuable for research focused on the mechanisms of guanosine receptors and the pathways of purine metabolism.
3′-Deoxyguanosine is a derivative of guanosine that primarily targets human purine nucleoside phosphorylase. This compound interacts through hydrogen bonding with key residues, including Glu201 and Asn243, and exhibits moderate displacement activity for [3H]-guanosine in rat meninges. 3′-Deoxyguanosine is valuable for research focused on the mechanisms of guanosine receptors and the pathways of purine metabolism.
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