Fig. 1 · Structure

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3-Hydroxyazetidine-Cyclohexanol

PROTAC Linker

3-Hydroxyazetidine-Cyclohexanol serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. Its chemical structure is designed to enhance the efficacy of targeted protein degradation, making it a valuable tool in drug discovery and development research. This compound is instrumental in the synthesis of ALK PROTACs, contributing to advancements in targeted therapies for various cancers.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1553176-51-4
Applications PROTAC Linker
Formula C9H17NO2
Molecular Weight 171.24
SMILES
OC1CN(C1)C2CCC(O)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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