3-Hydroxycoumarin is a potent inhibitor of tyrosinase and lipoxygenase, exhibiting an IC50 of 26 μM against recombinant human tyrosinase and a Ki of 3.39 μM. It also demonstrates effective inhibition of lipoxygenase with an IC50 of 9.5 μM. Additionally, 3-Hydroxycoumarin displays significant DPPH free radical scavenging activity (IC50 = 31.2 μM) and offers photoprotective benefits for sea urchin zygotes and embryos, making it a valuable reagent for research in enzymatic inhibition and oxidative stress studies.
3-Hydroxycoumarin is a potent inhibitor of tyrosinase and lipoxygenase, exhibiting an IC50 of 26 μM against recombinant human tyrosinase and a Ki of 3.39 μM. It also demonstrates effective inhibition of lipoxygenase with an IC50 of 9.5 μM. Additionally, 3-Hydroxycoumarin displays significant DPPH free radical scavenging activity (IC50 = 31.2 μM) and offers photoprotective benefits for sea urchin zygotes and embryos, making it a valuable reagent for research in enzymatic inhibition and oxidative stress studies.
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