Fig. 1 · Structure

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3-Hydroxyphloridzin

PTP1B Inhibitor

3-Hydroxyphloridzin is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), which plays a critical role in regulating insulin signaling. By modulating the phosphorylation levels of the insulin receptor, 3-Hydroxyphloridzin may enhance insulin sensitivity and has potential applications in the study of type 2 diabetes and related metabolic disorders. This compound is valuable for researchers investigating therapeutic strategies aimed at improving insulin action.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 30779-02-3
Applications PTP1B Inhibitor
Formula C21H24O11
Molecular Weight 452.41
Synonyms 3-Hydroxyphlorizin
SMILES
OC(C=C1CCC(C2=C(C=C(C=C2O)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O)=C(C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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