3-Mercaptopropionic acid NHS ester

Catalog No.: A81432
PROTAC Linker
3-Mercaptopropionic acid NHS ester functions as a linker in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating the conjugation of target proteins for degradation. This reagent enables the synthesis of innovative PROTACs by providing a reactive moiety for efficient attachment to both the ubiquitin ligase and the target protein. Its unique structure supports targeted proteolysis and enhances the specificity and efficacy of therapeutic interventions in protein homeostasis research.
Grouped product items
Size Price Stock Qty
100mg
$20.00
In stock
500mg
$45.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-Mercaptopropionic acid NHS ester functions as a linker in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating the conjugation of target proteins for degradation. This reagent enables the synthesis of innovative PROTACs by providing a reactive moiety for efficient attachment to both the ubiquitin ligase and the target protein. Its unique structure supports targeted proteolysis and enhances the specificity and efficacy of therapeutic interventions in protein homeostasis research.
Product Information
Catalog NumA81432
FormulaC7H9NO4S
Molecular Weight203.22
CAS Number117235-10-6
SMILESO=C(ON1C(CCC1=O)=O)CCS
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