Biological Activity
3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase).
Targets
Vps34 (HeLa cells) | PI3Kγ (HeLa cells) | |||
25 μM | 60 μM |
In vitro (25°C) | DMSO | 61 mg/mL (408.98 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | 4 mg/mL (26.81 mM) | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 30 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 67.02 mL | 335.12 mL | 670.24 mL |
0.5 mM | 13.4 mL | 67.02 mL | 134.05 mL |
1 mM | 6.7 mL | 33.51 mL | 67.02 mL |
5 mM | 1.34 mL | 6.7 mL | 13.4 mL |
*The above data is based on the productmolecular weight 149.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11151 |
---|---|
Actions | Inhibitor |
M. Wt | 149.2 |
Formula | C6H7N5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 5142-23-4 |
Synonyms | 3-MA |
SMILES | CN1C=NC(=C2C1=NC=N2)N |
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