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3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase).
Targets
| Vps34 (HeLa cells) | PI3Kγ (HeLa cells) | |||
| 25 μM | 60 μM |
| In vitro (25°C) | DMSO | 61 mg/mL (408.98 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 4 mg/mL (26.81 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 67.02 mL | 335.12 mL | 670.24 mL |
| 0.5 mM | 13.4 mL | 67.02 mL | 134.05 mL |
| 1 mM | 6.7 mL | 33.51 mL | 67.02 mL |
| 5 mM | 1.34 mL | 6.7 mL | 13.4 mL |
*The above data is based on the productmolecular weight 149.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A11151 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 149.2 |
| Formula | C6H7N5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 5142-23-4 |
| Synonyms | 3-MA |
| SMILES | CN1C=NC(=C2C1=NC=N2)N |
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