Biological Activity
3AC is a cell-permeable, selective inhibitor of SHIP1 polyphosphatase activity toward PIP3 (IC50 = 10 μM), but has no effect on SHIP2 or PTEN activity on PIP3.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.79 mL | 128.97 mL | 257.94 mL |
0.5 mM | 5.16 mL | 25.79 mL | 51.59 mL |
1 mM | 2.58 mL | 12.9 mL | 25.79 mL |
5 mM | 0.52 mL | 2.58 mL | 5.16 mL |
*The above data is based on the productmolecular weight 387.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A12817 |
---|---|
Actions | Inhibitor |
M. Wt | 387.69 |
Formula | C27H49N |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2206-20-4 |
Synonyms | 3-AC, 3 AC |
SMILES | CC(C)CCC[[email protected]@H](C)[[email protected]]1CC[[email protected]@]2([H])[[email protected]]3([H])CCC4C[[email protected]](N)CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]]12C |
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