3AC

Catalog No.: A12817

SHIP1 Inhibitor

3AC

3AC Chemical Structure

CAS NO. 2206-20-4

3AC is a cell-permeable, selective inhibitor of SHIP1 polyphosphatase activity toward PIP3 (IC50 = 10 μM), but has no effect on SHIP2 or PTEN activity on PIP3.

Availability: In stock

Package Price Qty
2 mg
$45.00
5 mg
$90.00
50 mg
$415.00
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Biological Activity

3AC is a cell-permeable, selective inhibitor of SHIP1 polyphosphatase activity toward PIP3 (IC50 = 10 μM), but has no effect on SHIP2 or PTEN activity on PIP3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.79 mL 128.97 mL 257.94 mL
0.5 mM 5.16 mL 25.79 mL 51.59 mL
1 mM 2.58 mL 12.9 mL 25.79 mL
5 mM 0.52 mL 2.58 mL 5.16 mL

*The above data is based on the productmolecular weight 387.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12817
Actions Inhibitor
CAS No. 2206-20-4
Formula C27H49N
M. Wt 387.69
Purity >98%
Synonyms 3-AC, 3 AC
SMILES CC(C)CCC[[email protected]@H](C)[[email protected]]1CC[[email protected]@]2([H])[[email protected]]3([H])CCC4C[[email protected]](N)CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]]12C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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