3β-Hydroxy-lup-20(29)-en-16-one is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting a notable selectivity for BChE with an IC50 value of 28.9 μM. This lupane derivative serves as a valuable tool in the study of cholinergic signaling pathways and triterpenoid research. Its inhibitory properties position it as a potential candidate for neurodegenerative disease research applications, particularly in disorders characterized by cholinergic dysregulation.
3β-Hydroxy-lup-20(29)-en-16-one is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting a notable selectivity for BChE with an IC50 value of 28.9 μM. This lupane derivative serves as a valuable tool in the study of cholinergic signaling pathways and triterpenoid research. Its inhibitory properties position it as a potential candidate for neurodegenerative disease research applications, particularly in disorders characterized by cholinergic dysregulation.
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