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4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate

PROTAC Linker

4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate serves as a critical linker in the development of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates targeted protein degradation, making it a valuable tool for studying protein function and regulation. It is notably utilized in the synthesis of PROTAC SMARCA2/4-degrader-27, advancing research in targeted therapies and cellular protein modulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2369046-75-1
Applications	PROTAC Linker
Formula	C₁₂H₁₆O₅S
Molecular Weight	272.32
SMILES	CS(OCCC1=CC=C(C=C1)C2OCCO2)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.