Fig. 1 · Structure
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4-(4-Aminophenyl)butanoic acid
PROTAC Linker
4-(4-Aminophenyl)butanoic acid is a versatile PROTAC linker that facilitates the construction of targeted protein degraders. By enabling the covalent attachment of ligands and E3 ligases, this compound plays a crucial role in the design of PROTACs aimed at selective protein degradation. Its application in biochemical research supports advances in drug discovery and development, particularly in targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 15118-60-2 |
| Applications | PROTAC Linker |
| Formula | C10H13NO2 |
| Molecular Weight | 179.22 |
| SMILES | O=C(O)CCCC1=CC=C(N)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.