Fig. 1 · Structure
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4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester
PROTAC Linker
4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester functions as a PROTAC linker, facilitating the creation of bifunctional small molecules that engage E3 ubiquitin ligases and target specific proteins for degradation. This compound is primarily utilized in the synthesis of CST905, contributing to advances in targeted protein degradation research. Its application enhances the development of novel therapeutics in various areas, including cancer and neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 470478-90-1 |
| Applications | PROTAC Linker |
| Formula | C21H33BN2O4 |
| Molecular Weight | 388.31 |
| SMILES | CC1(C)OB(C2=CC=C(N3CCN(C(OC(C)(C)C)=O)CC3)C=C2)OC1(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.