4,4'-Sulfonyldiphenol-d8 is a deuterium-labeled analog of 4,4'-Sulfonyldiphenol, which acts as an estrogen receptor agonist and can bind competitively to thyroid hormone receptors. This compound is implicated in various biological activities including the promotion of glioblastoma through the upregulation of the EZH2-mediated PI3K/AKT/mTOR pathway. Additionally, chronic exposure may lead to lipid accumulation and dyslipidemia in liver tissues, potentially contributing to obesity at low doses. Research applications of 4,4'-Sulfonyldiphenol-d8 include studies on endocrine disruption, lipid metabolism disorders, and the investigation of inflammatory responses in the intestinal microbiome.
4,4'-Sulfonyldiphenol-d8 is a deuterium-labeled analog of 4,4'-Sulfonyldiphenol, which acts as an estrogen receptor agonist and can bind competitively to thyroid hormone receptors. This compound is implicated in various biological activities including the promotion of glioblastoma through the upregulation of the EZH2-mediated PI3K/AKT/mTOR pathway. Additionally, chronic exposure may lead to lipid accumulation and dyslipidemia in liver tissues, potentially contributing to obesity at low doses. Research applications of 4,4'-Sulfonyldiphenol-d8 include studies on endocrine disruption, lipid metabolism disorders, and the investigation of inflammatory responses in the intestinal microbiome.
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