Fig. 1 · Structure
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4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
PROTAC Linkers
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol functions as a versatile alkyl chain-based linker for PROTAC (proteolysis-targeting chimera) synthesis. This compound enables targeted protein degradation by connecting an E3 ligase with a target protein, facilitating the modulation of protein levels within a cellular context. It is suitable for research applications in the development of novel therapeutic agents and the study of protein homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58884-35-8 |
| Applications | PROTAC Linkers |
| Formula | C9H8N4O |
| Molecular Weight | 188.19 |
| SMILES | OC1=CC=C(C2=NN=C(C)N=N2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.