Fig. 1 · Structure

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4-(Aminomethyl)bicyclo2.2.2Octan-1-ol

PROTAC Linker

4-(Aminomethyl)bicyclo[2.2.2]Octan-1-ol is a versatile PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a crucial component in the synthesis of bifunctional molecules that induce targeted protein degradation, enabling enhanced specificity and efficacy in therapeutic applications. Its structural properties promote efficient conjugation to both target proteins and E3 ligases, making it valuable for advancing research in targeted protein degradation strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 72948-92-6
Applications PROTAC Linker
Formula C9H17NO
Molecular Weight 155.24
SMILES
OC12CCC(CN)(CC1)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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