Fig. 1 · Structure
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4-Azido-2,3,5,6-tetrafluorobenzoic Acid
DNA Probe
4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent characterized by its azide functionality, making it suitable for applications in DNA probing. This compound forms complexes with FAM-labeled DNA probes, facilitating investigations into biological receptors through photoaffinity labeling. N3-TFBA is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) in conjunction with alkyne-containing molecules, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized substrates.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 122590-77-6 |
| Applications | DNA Probe |
| Formula | C7HF4N3O2 |
| Molecular Weight | 235.10 |
| Synonyms | N3-TFBA |
| SMILES | [N-]=[N+]=NC1=C(C(F)=C(C(F)=C1F)C(O)=O)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.