Fig. 1 · Structure
Documents & Downloads
4-Bromo-1-trimethylsilyl-1-butyne
PROTAC Linker
4-Bromo-1-trimethylsilyl-1-butyne serves as a versatile linker for the development of PROTAC (proteolysis-targeting chimera) molecules. Its unique structural features facilitate the conjugation of target ligands, thereby enabling the selective degradation of proteins through the ubiquitin-proteasome system. This compound is critical for advancing research in targeted protein degradation and enhancing therapeutic strategies in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 69361-41-7 |
| Applications | PROTAC Linker |
| Formula | C7H13BrSi |
| Molecular Weight | 205.17 |
| SMILES | BrCCC#C[Si](C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.