Fig. 1 · Structure
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4-Bromo-2-hydroxypyridine
Cat. No.
A88107
CAS
36953-37-4
Intermediate
4-Bromo-2-hydroxypyridine serves as an important intermediate in organic synthesis, specifically for the development of positive allosteric modulators of the M1 muscarinic acetylcholine receptor (M1 mAChR). Its biological activity makes it a valuable compound in research related to neurodegenerative disorders such as Alzheimer's disease and psychiatric conditions like schizophrenia. This reagent is essential for advancing studies aimed at understanding and targeting cholinergic dysfunction in these diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 36953-37-4 |
| Applications | Intermediate |
| Formula | C5H4BrNO |
| Molecular Weight | 174.00 |
| Synonyms | 4-Bromo-2-pyridone |
| SMILES | OC1=NC=CC(Br)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.