Fig. 1 · Structure
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4-Bromobutanoic acid tert-butyl ester
PROTAC Linker
4-Bromobutanoic acid tert-butyl ester functions as a PROTAC linker, facilitating the synthesis of PROTACs for targeted protein degradation. This compound plays a critical role in modulating protein levels within cells, enabling the study of protein function and potential therapeutic developments. Its incorporation into PROTACs aids in the design of innovative approaches for drug discovery and development in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 110661-91-1 |
| Applications | PROTAC Linker |
| Formula | C8H15BrO2 |
| Molecular Weight | 223.11 |
| Synonyms | tert-Butyl 4-Bromobutyrate |
| SMILES | O=C(OC(C)(C)C)CCCBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.