Fig. 1 · Structure

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4-Bromobutyronitrile

PROTAC Linker

4-Bromobutyronitrile is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its structural attributes enable effective conjugation to both target proteins and E3 ligases, promoting targeted degradation pathways. This compound is essential for researchers investigating innovative therapeutic strategies in drug discovery and cellular protein regulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 5332-06-9
Applications PROTAC Linker
Formula C4H6BrN
Molecular Weight 148.00
SMILES
N#CCCCBr

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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