Fig. 1 · Structure
Documents & Downloads
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline
Synthetic Intermediate
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a synthetic intermediate utilized in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and various anticancer agents. This compound serves as a crucial precursor for the development of epidermal growth factor receptor (EGFR) inhibitors such as Erlotinib, contributing to antiproliferative effects in cancer research. Its role as a building block makes it valuable in advancing therapeutic strategies targeting tumor growth and metastasis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 183322-18-1 |
| Applications | Synthetic Intermediate |
| Formula | C14H17ClN2O4 |
| Molecular Weight | 312.75 |
| SMILES | ClC1=NC=NC2=C1C=C(OCCOC)C(OCCOC)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.