Fig. 1 · Structure
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4-Chlorochalcone
Monoamine Oxidase Inhibitor
4-Chlorochalcone is a selective monoamine oxidase inhibitor, demonstrating an IC50 of 0.082 μM against hMAO-B and 9.95 μM against hMAO-A. This compound also shows inhibitory activity towards acetylcholinesterase, with an IC50 of 2.79 μM. As a chalcone derivative, 4-Chlorochalcone is valuable for research focused on neurodegenerative diseases and the modulation of neurotransmitter levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 956-04-7 |
| Applications | Monoamine Oxidase Inhibitor |
| Formula | C15H11ClO |
| Molecular Weight | 242.70 |
| SMILES | O=C(C=CC1=CC=C(Cl)C=C1)C=2C=CC=CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.