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4-(Chloromethyl)phenylacetic Acid

PROTAC Linker

4-(Chloromethyl)phenylacetic Acid serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound enhances targeted protein degradation by effectively linking target proteins to E3 ubiquitin ligases. Its application in the synthesis of PROTACs allows researchers to explore novel therapeutic strategies in areas such as cancer and neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	56066-91-2
Applications	PROTAC Linker
Formula	C₉H₉ClO₂
Molecular Weight	184.62
SMILES	O=C(O)CC1=CC=C(C=C1)CCl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.