Fig. 1 · Structure
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4-Ethylphenyl sulfate
Gut Microbial Metabolite
4-Ethylphenyl sulfate is a gut microbial metabolite that exhibits brain-penetrant properties. It has been shown to downregulate Bcl2 and upregulate Bax, leading to induced apoptosis in cancer cells through the endogenous apoptotic pathway. Additionally, 4-Ethylphenyl sulfate causes G2/M cell cycle arrest and increases reactive oxygen species (ROS) production. In neurobiology research, it impairs oligodendrocyte maturation and disrupts oligodendrocyte-neuron interactions, resulting in decreased axonal myelination and a shift towards immature precursor cells, which correlates with altered neural activity and anxiety-like behaviors in mice.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 85734-98-1 |
| Applications | Gut Microbial Metabolite |
| Formula | C8H10O4S |
| Molecular Weight | 202.23 |
| SMILES | O=S(O)(OC1=CC=C(CC)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.