Fig. 1 · Structure

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4-Hydroxybutyl 4-methylbenzenesulfonate

PROTAC Linker

4-Hydroxybutyl 4-methylbenzenesulfonate serves as a PROTAC linker utilized in the development of targeted protein degradation strategies. This compound facilitates the efficient conjugation of target proteins to E3 ligases, promoting their ubiquitination and subsequent degradation. Its utility in synthesizing PROTACs makes it valuable for research focused on modulating protein levels in various biological contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 6972-09-4
Applications PROTAC Linker
Formula C11H16O4S
Molecular Weight 244.31
SMILES
O=S(=O)(OCCCCO)C1=CC=C(C=C1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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