4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, functioning primarily as a β1 and β2 adrenergic receptor antagonist. This compound exhibits comparable potency to its parent drug, inhibiting β1-adrenergic receptors with a pA2 value of 8.24 and β2-adrenergic receptors with a pA2 value of 8.26. Additionally, 4-Hydroxypropranolol hydrochloride possesses intrinsic sympathomimetic activity, membrane stabilizing properties, and significant antioxidant effects, making it valuable in research related to cardiovascular diseases and stress response mechanisms.
4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, functioning primarily as a β1 and β2 adrenergic receptor antagonist. This compound exhibits comparable potency to its parent drug, inhibiting β1-adrenergic receptors with a pA2 value of 8.24 and β2-adrenergic receptors with a pA2 value of 8.26. Additionally, 4-Hydroxypropranolol hydrochloride possesses intrinsic sympathomimetic activity, membrane stabilizing properties, and significant antioxidant effects, making it valuable in research related to cardiovascular diseases and stress response mechanisms.
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