Fig. 1 · Structure
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4-(Piperidin-4-yl)oxypiperidine-1-carboxylic acid tert-butyl ester
PROTAC Linker
4-[(Piperidin-4-yl)oxy]piperidine-1-carboxylic acid tert-butyl ester is a versatile PROTAC linker that facilitates the development of targeted protein degradation strategies. This compound plays a crucial role in the synthesis of bifunctional molecules designed to promote the ubiquitination and subsequent degradation of specific proteins within cellular contexts. Its application is essential for researchers investigating proteolysis-targeting chimeras (PROTACs) in varied biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 845305-83-1 |
| Applications | PROTAC Linker |
| Formula | C15H28N2O3 |
| Molecular Weight | 284.40 |
| SMILES | O=C(OC(C)(C)C)N1CCC(OC2CCNCC2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.